(Kadamba Kanana Swami, 9 January 2017, Brisbane, Australia, Srimad Bhagavatam 1.1.6)
We may think that we are free because we are making our own choices according to our own liking. But what we fail to see is that when we are not following the four regulative principles closely, we are actually in the grip of kali. This is why Srila Prabhupada formalised the four regulative principles. Pānaṁ (intoxication), dyūtam (gambling), striyaṁ (illicit sex) and śunām (meat eating) are all mentioned as the four types of adharma (irreligion). Therefore, Prabhupada pointed out that we must follow the four regulative principles because otherwise, we are not actually in control of our own mind, but kali will be in control of our mind.